Anal HPV

HPV (Human Papillomavirus) is a skin virus that is transmitted through intimate contact. HPV can be either low-risk or high-risk. High-risk strains may result in 6 different HPV-related cancers including anal cancer. According to the Journal of National Cancer Institute; 107(6), HPV associated anal cancer affects approximately 3,286 women and 1,916 men every year in the United States.

The majority of HPV-associated cancers are linked to just two types of HPV: types 16 and 18. There are about 16 high-risk types that have been identified, and there are over 100 different types of HPV overall. 40 HPV strains are sexually transmitted. The term ‘high-risk’ means that these types of HPV are more likely than other types to cause cancer.  HPV types 16 and 18 are responsible for 92% of anal cancers.

HPV 6 and 11 are low risk viruses and although they do not cause cancer they may cause genital warts in the anus. These warts are usually asymptomatic, but can be painful. There is no cure for HPV, but warts may be treated and removed.

Collection protocol:

WCPL Anal Cytology Collection Animation (QuickTime Video Format)

Sample report:

HPV16_Anal_Positive

References:

http://www.mayoclinic.org/diseases-conditions/anal-cancer/home/ovc-20233197

http://www.analcancerfoundation.org