Molecular Diagnostics

WCPL’s core area of expertise lies with Molecular Genetics and Diagnostics using true polymerase chain reactions and in the diagnostic interpretation of biopsies and cytology preparations. Our main client groups include individual physicians, patients, hospitals, surgery centers and university health centers.

To learn more about WCPL and how the services we offer can benefit you, please peruse the rest of this site.

Molecular Diagnostics – HPV Detection and Genotyping, Chlamydia and Neisseria detection, Herpes Simplex Viruses I and II, Vaginal Inflammation Panel, Yeast Panel, Group B Streptococcus, and 3q-26.

The Human Genome Project has set the stage for countless advancements in our understanding of human DNA and its role in the diagnosis of disease. Nowhere is this truer than in the area of women’s health. Pathologists and clinicians are increasingly turning to the power of molecular geneticsfor early and accurate diagnoses of disease.

The Advantages of Molecular Diagnostics

DNA can be reliably extracted from a variety of sources, including blood, tissue, or cells from a liquid Pap test, to produce a sample that can be screened for disease. Using molecular diagnostics, physicians can diagnose diseases earlier, or even before they occur. Molecular testing offers superior sensitivity and specificity, as well as added diagnostic utility when combined with cytology results.

PCR: The Gold Standard for Molecular Testing

Polymerase Chain Reaction (PCR) is the most broadly applicable method used in gene-based testing. The basis of PCR is the use of an enzyme to amplify specific parts of a gene, thereby mimicking what occurs in vivo during DNA synthesis.

The benefits of PCR include increased flexibility, sensitivity, specificity and reliability.PCR provides appropriate clinical sensitivity by amplifying small amounts DNA to pick up minute disease signals, allowing for efficient interpretation of DNA mutations. At the same time, PCR’s specificity pinpoints a particular disease at the exact location of the change in the DNA sequence.

In just a few hours, PCR-based testing gives pathologists and clinicians the ability to screen for a host of disorders efficiently and accurately with superior analytic performance. PCR allows pathologists to perform a large number of tests, scalable to the market, and offers proven technology for reimbursable clinical laboratory testing.